TY - CHAP M1 - Book, Section TI - Cancer: An Overview A1 - Jacob, Molly A1 - Varghese, Joe A1 - Weil, P. Anthony A2 - Rodwell, Victor W. A2 - Bender, David A. A2 - Botham, Kathleen M. A2 - Kennelly, Peter J. A2 - Weil, P. Anthony PY - 2018 T2 - Harper's Illustrated Biochemistry, 31e AB - OBJECTIVESAfter studying this chapter, you should be able to:Present an overview of carcinogenesis and important biochemical and genetic features of cancer cells.Describe important properties of oncogenes and tumor suppressor genes and their role in carcinogenesis.Describe the important characteristics of cancer cells that distinguish them from normal cells.Briefly describe the concepts of genomic instability, aneuploidy, and angiogenesis in tumor formation and growth.Discuss the relevance of tumor markers.Outline how understanding of the biology of cancer has led to the development of various new therapies. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/29 UR - accessmedicine.mhmedical.com/content.aspx?aid=1160193846 ER -