TY - CHAP M1 - Book, Section TI - Biologic Oxidation A1 - Botham, Kathleen M. A1 - Mayes, Peter A. A2 - Rodwell, Victor W. A2 - Bender, David A. A2 - Botham, Kathleen M. A2 - Kennelly, Peter J. A2 - Weil, P. Anthony PY - 2018 T2 - Harper's Illustrated Biochemistry, 31e AB - OBJECTIVESAfter studying this chapter, you should be able to:Explain the meaning of redox potential and how it can be used to predict the direction of flow of electrons in biologic systems.Identify the four classes of enzymes (oxidoreductases) involved in oxidation and reduction reactions.Describe the action of oxidases and provide examples of where they play an important role in metabolism.Indicate the two main functions of dehydrogenases and explain the importance of nicotinamide adenine dinucleotide (NAD)- and riboflavin-linked dehydrogenases in metabolic pathways such as glycolysis, the citric acid cycle, and the respiratory chain.Identify the two types of enzymes classified as hydroperoxidases; indicate the reactions they catalyze and explain why they are important.Give the two steps of reactions catalyzed by oxygenases and identify the two subgroups of this class of enzymes.Appreciate the role of cytochrome P450 in drug detoxification and steroid synthesis.Describe the reaction catalyzed by superoxide dismutase and explain how it protects tissues from oxygen toxicity. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - accessmedicine.mhmedical.com/content.aspx?aid=1162228786 ER -