TY - CHAP M1 - Book, Section TI - Implantation and Placental Development A1 - Cunningham, F. Gary A1 - Leveno, Kenneth J. A1 - Bloom, Steven L. A1 - Dashe, Jodi S. A1 - Hoffman, Barbara L. A1 - Casey, Brian M. A1 - Spong, Catherine Y. PY - 2018 T2 - Williams Obstetrics, 25e AB - Almost immediately after the implantation of the ovum, its trophoblast begins to proliferate and invade the surrounding decidual tissue. As it does so, it breaks through the walls of the maternal capillaries, from which the blood escapes and forms cavities, which are bounded partly by trophoblast and partly by decidua. The maternal blood spaces established in this manner represent the earliest stages of the intervillous blood spaces of the future placenta.—J. Whitridge Williams (1903) SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - accessmedicine.mhmedical.com/content.aspx?aid=1160772378 ER -