TY - CHAP M1 - Book, Section TI - TRICUSPID AND PULMONARY VALVE DISEASE A1 - Chikwe, Joanna Y. A1 - Castillo, Javier G. A2 - Fuster, Valentin A2 - Harrington, Robert A. A2 - Narula, Jagat A2 - Eapen, Zubin J. PY - 2017 T2 - Hurst's The Heart, 14e AB - Mild tricuspid valve disease is common, and usually clinically silent.1 Moderate and severe tricuspid regurgitation, however, are increasingly recognized as an important marker of morbidity and mortality.2 By far the commonest etiology is secondary or functional tricuspid regurgitation, where the valve leaflets are structurally normal, and regurgitation is primarily a result of annular dilatation in the setting of right or left heart dysfunction or dilatation, or pulmonary hypertension.3 Secondary tricuspid regurgitation is a very dynamic lesion, commonly seen in patients with left-sided valvular disease, ischemic heart disease, or atrial fibrillation. Primary tricuspid disease is most commonly a result of endocarditis, carcinoid heart disease, or rheumatic valve disease, with lead- and catheter-related pathology from cardiac devices as an increasingly recognized cause. Apart from congenital lesions involving the pulmonary valve or the right ventricular infundibulum and carcinoid heart disease, pulmonary valve disease as an acquired condition in adults is extremely rare. The pulmonary valve is the least commonly involved in infectious processes such as rheumatic fever and bacterial endocarditis. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - accessmedicine.mhmedical.com/content.aspx?aid=1161731758 ER -