TY - CHAP M1 - Book, Section TI - Disorders of Organelles A1 - Schaefer, G. Bradley A1 - Thompson, Jr., James N. PY - 2017 T2 - Medical Genetics: An Integrated Approach AB - The functions of cell organelles like the nucleus and mitochondria are critical to the processes on which life depends. But that does not mean they are easy to study. From a general biology course you probably learned facts like a nucleus controls the growth and reproduction of a cell and ribosomes are the sites of protein synthesis (Figure 13-1). But for a moment, take a step back and ask a more basic question, "How do we know these things?" Just seeing the microscopic structures inside a cell is hard enough. How can we know the way they actually work? For medical genetics, the next question is then obvious. What are the medical effects of a genetic change in the structure or activity of a cell organelle? Can that knowledge lead to appropriate treatment? SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/29 UR - accessmedicine.mhmedical.com/content.aspx?aid=1147723358 ER -