TY  - CHAP
M1  - Book, Section
TI  - Delirium in the Intensive Care Unit
A1  - Hsieh, S. Jean
A2  - Oropello, John M.
A2  - Pastores, Stephen M.
A2  - Kvetan, Vladimir
PY  - 1
T2  - Critical Care
AB  - KEY  POINTSICU  delirium  is  a  common  form  of  acute  “brain  failure”  that  is  associated  with  significant  morbidity  and  mortality.  Delirium  has  a  dose  response  relationship  with  poor  outcomes:  the  longer  the  delirium  duration,  the  poorer  the  outcome.Delirium  can  be  missed  in  up  to  75%  of  patients  if  a  screening  tool  is  not  used,  likely  because  of  the  high  prevalence  of  hypoactive  delirium.Early  diagnosis  of  delirium  is  imperative  for  effective  delivery  of  delirium  reduction  strategies.  Therefore,  delirium  assessments  should  be  part  of  the  ICU  admission  physical  exam  and  should  be  incorporated  into  the  daily  work-flow.ICU-acquired  risk  factors  for  delirium  (eg,  oversedation,  immobilization,  uncontrolled  pain)  are  potentially  modifiable  and  closely  interrelated.  Implementation  of  nonpharmacologic  multicomponent  strategies  to  prevent  and  reduce  delirium  on  an  ICU-wide  scale  (eg,  targeted  light/no  sedation,  early  rehabilitation)  can  shorten  the  duration  of  ICU  delirium  and  improve  clinical  outcomes.Pharmacologic  prevention  and  treatment  of  delirium  (eg,  dexmedetomidine  over  benzodiazepines  for  sedation)  can  be  considered  for  individual  patients,  although  the  efficacy  of  these  strategies  is  still  unclear.  
SN  - 
PB  - McGraw-Hill Education
CY  - New York, NY
Y2  - 2024/04/19
UR  - accessmedicine.mhmedical.com/content.aspx?aid=1136416382
ER  -