TY - CHAP M1 - Book, Section TI - Megaloblastic Anemias A1 - Bunn, H. Franklin A1 - Heeney, Matthew A2 - Aster, Jon C. A2 - Bunn, H. Franklin PY - 2016 T2 - Pathophysiology of Blood Disorders, 2e AB - LEARNING OBJECTIVESAfter studying this chapter, you should be able to:Draw a simple scheme outlining the key biochemical reactions involving cobalamin (vitamin B12) and folate.Understand how cobalamin and folate are absorbed from the gut and transported in plasma.Explain the mechanisms that cause megaloblastic morphology in the bone marrow and blood and describe these features.Describe the causes and treatment of cobalamin deficiency.Describe the causes and treatment of folate deficiency. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - accessmedicine.mhmedical.com/content.aspx?aid=1188899771 ER -