TY  - CHAP
M1  - Book, Section
TI  - Ankylosing Spondylitis
A1  - Kasper, Dennis L.
A1  - Fauci, Anthony S.
A1  - Hauser, Stephen L.
A1  - Longo, Dan L.
A1  - Jameson, J. Larry
A1  - Loscalzo, Joseph
PY  - 2016
T2  - Harrison's Manual of Medicine, 19e
AB  - Ankylosing  spondylitis  (AS)  belongs  to  the  family  of  spondyloarthritides  that  also  includes  reactive  arthritis  (Chap.  162),  psoriatic  arthritis  (Chap.  161),  enteropathic  arthritis  (Chap.  165)  juvenile-onset  spondyloarthritis,  and  undifferentiated  spondyloarthritis.  Classification  criteria  based  on  their  main  clinical  features  of  axial  spondyloarthritis  (Table  160-1)  and  peripheral  spondyloarthritis  (Table  160-2)  have  been  developed  that  aide  in  early  identification.  AS  is  a  chronic  and  progressive  inflammatory  disease  of  the  axial  skeleton  with  sacroiliitis  (usually  bilateral)  as  its  hallmark.  Peripheral  joints  and  extra-articular  structures  may  also  be  affected.  Most  frequently  presents  in  second  or  third  decade  more  commonly  in  men;  strong  association  with  histocompatibility  antigen  HLA-B27.  
SN  - 
PB  - McGraw-Hill Education
CY  - New York, NY
Y2  - 2024/04/18
UR  - accessmedicine.mhmedical.com/content.aspx?aid=1128787415
ER  -