TY - CHAP M1 - Book, Section TI - Interstitial Lung Disease A1 - Kasper, Dennis L. A1 - Fauci, Anthony S. A1 - Hauser, Stephen L. A1 - Longo, Dan L. A1 - Jameson, J. Larry A1 - Loscalzo, Joseph PY - 2016 T2 - Harrison's Manual of Medicine, 19e AB - Interstitial lung diseases (ILDs) are a group of >200 disease entities characterized by diffuse lung parenchymal abnormalities. ILDs can be classified into two major groups: (1) diseases associated with predominant inflammation and fibrosis, and (2) diseases with predominantly granulomatous reaction in interstitial or vascular areas (Table 134-1). ILDs are nonmalignant and noninfectious, and they are typically chronic. The differential diagnosis of ILDs often includes infections (e.g., atypical mycobacteria, fungi) and malignancy (e.g., lymphangitic carcinomatosis). One of the most common ILDs associated with a granulomatous reaction, sarcoidosis, is discussed in Chap. 166. Many ILDs are of unknown etiology; however, some ILDs are known to be associated with specific environmental exposures including asbestos, radiation therapy, and organic dusts. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - accessmedicine.mhmedical.com/content.aspx?aid=1128786523 ER -