TY - CHAP M1 - Book, Section TI - Digitalis Glycosides A1 - Levine, Michael A1 - Skolnik, Aaron B. A2 - Tintinalli, Judith E. A2 - Stapczynski, J. Stephan A2 - Ma, O. John A2 - Yealy, Donald M. A2 - Meckler, Garth D. A2 - Cline, David M. PY - 2016 T2 - Tintinalli’s Emergency Medicine: A Comprehensive Study Guide, 8e AB - The medicinal benefits of cardiac glycosides have been recognized for centuries, and even with other alternative medications, digitalis preparations, such as digoxin, are still used for the treatment of atrial fibrillation and symptomatic congestive heart failure.1 In addition to availability as pharmaceuticals, cardiac glycosides are also found in plants such as foxglove, oleander, red squill, and lily of the valley. Similar cardioactive steroids are also found in the skin of toads in the Bufonidae family and in some herbal medications. Despite declining use of digoxin, the prevalence of patients diagnosed with digoxin toxicity has remained constant, and the use of digoxin-specific antibody fragments has increased.2 Digitoxin, a cardiac glycoside similar in structure to digoxin but with a longer half-life, is no longer commercially available in the United States, but is available in Canada and elsewhere in the world. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - accessmedicine.mhmedical.com/content.aspx?aid=1132928898 ER -