TY - CHAP M1 - Book, Section TI - Nonalcoholic Fatty Liver Disease A1 - Cohen, David E. A1 - Anania, Frank A. A2 - Greenberger, Norton J. A2 - Blumberg, Richard S. A2 - Burakoff, Robert PY - 2016 T2 - CURRENT Diagnosis & Treatment: Gastroenterology, Hepatology, & Endoscopy, 3e AB - ESSENTIALS OF DIAGNOSISNonalcoholic fatty liver disease (NAFLD) is the term that represents a broad spectrum of disease ranging from simple steatosis to nonalcoholic steatohepatitis (NASH) and steatofibrosis.NAFLD is commonly associated with the metabolic syndrome, obesity, type 2 diabetes, and dyslipidemia; 80% of patients with the metabolic syndrome have NAFLD.Patients generally present without clinical symptoms but with mild transaminase elevations; NAFLD is the most common cause of increased serum transaminase levels.NAFLD is a clinical diagnosis after exclusion of other causes of liver disease.Ultrasound, computed tomography (CT), and magnetic resonance imaging (MRI) are useful for the detection.Liver biopsy is currently required to distinguish NASH from NAFLD. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/29 UR - accessmedicine.mhmedical.com/content.aspx?aid=1119990644 ER -