TY - CHAP M1 - Book, Section TI - Alcoholic Liver Disease A1 - Baffy, Gyorgy A1 - Krisko, Tibor A2 - Greenberger, Norton J. A2 - Blumberg, Richard S. A2 - Burakoff, Robert PY - 2016 T2 - CURRENT Diagnosis & Treatment: Gastroenterology, Hepatology, & Endoscopy, 3e AB - ESSENTIALS OF DIAGNOSISHarmful alcohol consumption is defined as more than 4 drinks on any single day or more than 14 drinks per week for men, while for women the threshold is more than 3 drinks on any single day or more than 7 drinks per week.In the United States, a standard drink is defined as any drink that contains about 14 g of pure ethyl alcohol.More than 60% of adult Americans consume alcohol in a more or less regular fashion, and it is estimated that 18 million Americans have an alcohol use disorder.The spectrum of alcoholic liver disease ranges from alcoholic steatosis to alcoholic cirrhosis, while alcoholic hepatitis may occur episodically in the absence or presence of advanced liver disease.Virtually everyone with excessive alcohol intake has alcoholic steatosis, while 10–15% of the affected population develop alcoholic cirrhosis and 10–35% develop one or more episodes of symptomatic alcoholic hepatitis.Patients with alcoholic liver disease are at increased risk of hepatocellular cancer, with an incidence rate of 1–2% per year among patients with cirrhosis.Alcoholic liver injury is suggested by increased serum aspartate aminotransferase (AST) and alanine aminotransferase (ALT) levels with an AST/ALT ratio exceeding 2.0. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - accessmedicine.mhmedical.com/content.aspx?aid=1119990566 ER -