TY  - CHAP
M1  - Book, Section
TI  - Eosinophilic Esophagitis
A1  - Greenberger, Norton J.
A2  - Greenberger, Norton J.
A2  - Blumberg, Richard S.
A2  - Burakoff, Robert
PY  - 2016
T2  - CURRENT Diagnosis & Treatment: Gastroenterology, Hepatology, & Endoscopy, 3e
AB  - ESSENTIALS  OF  DIAGNOSISIn  adults,  a  major  symptom  is  recurrent  dysphagia,  often  with  food  impaction;  mean  duration  of  symptoms  before  treatment  is  4–6  years.Esophageal  biopsy  shows  dense  eosinophilic  infiltration  (≥15  eosinophils  per  high-power  field  [HPF]).Full  diagnostic  criteria  are  (1)  clinical  symptoms  of  esophageal  dysfunction;  (2)  increased  eosinophils  in  esophageal  mucosal  biopsies;  (3)  secondary  causes  of  esophageal  eosinophilia  have  been  excluded;  (4)  lack  of  sustained  response  to  high-dose  proton  pump  inhibition  treatment  or  normal  pH  monitoring  of  the  distal  esophagus;  (5)  response  to  treatment  (elimination  diet,  topical  glucocorticoids)  supports  the  diagnosis.  
SN  - 
PB  - McGraw-Hill Education
CY  - New York, NY
Y2  - 2024/04/19
UR  - accessmedicine.mhmedical.com/content.aspx?aid=1119986965
ER  -