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1° prevention: Disease prevention measures such as counseling for at-risk behaviors, immunizations, and chemoprevention that are taken before the disease develops.
2° prevention: Defined as early detection and treatment of asymptomatic disease, including risk assessment.
3° prevention: Management of chronic diseases to prevent or minimize complications.
Characteristics that make a disease appropriate for screening include:
Disease leads to significant morbidity and mortality.
Effective treatment is available.
Disease is detectable in the asymptomatic period.
Testing is accurate and simple.
Treatment administered during the asymptomatic period yields a better outcome than treatment in the symptomatic period.
Characteristics of risk factors that would be appropriate for screening are:
High prevalence of the risk factor in the population to be screened.
Large portions of those with the risk factor are unidentified.
Associated disease should have a high incidence in the population to be screened.
Disease should have serious consequences.
Readily available treatment that can modify the risk factor.
Risk modification should ↓ disease incidence.
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Table 2.1 outlines common adult immunizations and their indications. For information on immunization of pediatric populations, refer to the Child and Adolescent Medicine chapter.
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