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A 62-year-old man with type 2 diabetes for 15 years presents with history of erythematous, hot, swollen right foot for 2 weeks (Figure 212-1). He is on multiple medications for management of his diabetes, but it is not successfully controlled. The patient does not recall any trauma to the foot. Three days ago, he noticed pain in his foot. He denies fever or chills. The radiograph of his foot (Figure 212-2) shows midfoot osteopenia, an early sign of acute Charcot arthropathy.

Figure 212-1

Charcot arthropathy in the right foot. Notice the swelling and discoloration compared to the contralateral side. (Courtesy of Javier La Fontaine, DPM.)

Figure 212-2

Anterior-posterior view of same foot demonstrating midfoot osteopenia, an early sign of acute Charcot arthropathy. (Courtesy of Javier La Fontaine, DPM.)

Charcot arthropathy is an uncommon foot complication in patients with neuropathy. Patients often present with pain, swelling, and erythema, similar to the presentation with a foot infection. Patients may have a rockerbottom foot deformity. Radiographs confirm the diagnosis.

Charcot foot, Charcot neuroarthropathy.

The incidence of Charcot arthropathy in diabetes ranges from 0.1% to 5%.1

Charcot arthropathy is a gradual destruction of the joint in patients with neurosensory loss, most commonly seen in patients with diabetic neuropathy.2 The pathogenesis is unknown. Proposed theories include:

  • Neurotraumatic theory—Following sensory-motor neuropathy, the resulting sensory loss and muscle imbalance induces abnormal stress in the bones and joints of the affected limb, leading to bone destruction.
  • Neurovascular theory—Following the development of autonomic neuropathy there is an increased blood flow to the extremity, resulting in osteopenia from a mismatch in bone reabsorption and synthesis.
  • Stretching of the ligaments because of joint effusion may lead to joint subluxation.
  • It is most likely that Charcot arthropathy involves all of the above mechanisms together.

  • Advanced peripheral neuropathy.
  • Micro- or macrotrauma.
  • Microangiopathy.
  • Nephropathy.

The diagnosis of Charcot arthropathy is suspected based on the presentation and confirmed with imaging.

Clinical Features

  • Red, hot, swollen foot (Figure 212-1).
  • Even with neurosensory loss, 71% of patients present with the chief complaint of pain.3
  • Rockerbottom foot deformity is a classic finding of this entity (Figure 212-3).
  • Patients may present with an open wound in the plantar aspect of the foot, which may complicate the diagnosis between Charcot arthropathy and infection.

Figure 212-3

Lateral view of the right foot demonstrating the classic rockerbottom deformity. (Courtesy of Javier La Fontaine, DPM.)


Radiographs are imperative for diagnosis.

  • Arch collapse within ...

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