A 78-year-old white woman presents with loss of central vision that has gradually worsened over the last 6 months. Fully independent before, she can no longer drive and has difficulty with activities of daily living. Her peripheral vision remains normal. Funduscopic examination reveals macular depigmentation and drusen (yellowish-colored subretinal deposits on the macula) (Figure 23-1). She is diagnosed with dry, age-related macular degeneration. After her physician discusses the available information about antioxidants and therapeutic options, she decides to start antioxidants and see an ophthalmologist to discuss laser, surgical, or medical treatments.