1. Blanpain C, Fuchs E: Epidermal homeostasis: A balancing act of stem cells in the skin. Nat Rev Mol Cell Biol 10:207-217, 2009
2. Kaur P: Interfollicular Epidermal stem cells: Identification, challenges, potential. J Invest Dermatol 126:1450-1458, 2006
3. Lajtha L: Stem cell concepts. Differentiation 14:23-34, 1979
4. Bickenbach JR: Identification and behavior of label-retaining cells in oral mucosa and skin. J Dent Res 60:1611-1620, 1981
5. Mackenzie IC: Relationship between mitosis and ordered structure of the stratum corneum in mouse skin. Nature 226:653-655, 1970
6. Morris RJ et al: Subpopulations of primary adult murine epidermal basal cells sedimented on density gradients. Cell Tissue Kinet 23:587-602, 1990
7. Triel C et al: Side population cells in human and murine epidermis lack stem cell characteristics. Exp Cell Res 295:79-90, 2004
8. Rheinwald JG, Green H: Serial cultivation of strains of human epidermal keratinocytes: The formation of keratinizing colonies from single cells. Cell 6:331-344, 1975
9. Morris RJ et al: Quantitation of primary in vitro clonogeneic keratinocytes from normal adult murine epidermis, following initiation, and during promotion of epidermal tumors. Cancer Res 48:6285-6290, 1988
10. Jones PH, Watt FM: Separation of human stem cells from transit amplifying cells on the basis of differences in integrin function and expression. Cell 73:713-724, 1993
11. Cai J, Weiss ML, Rao MS: In search of “stemness”. Exp Hematol 32:585-598, 2004
12. Cairns J: Mutation selection and the natural history of cancer. Nature 255:197-200, 1975
13. Cairns J: Cancer and the immortal strand hypothesis. Genetics 174:1069-1072, 2006
14. Booth BW, Boulanger CA, Smith GH: Selective segregation of DNA strands persists in long label retaining mammary cells during pregnancy. Breast Cancer Res, http://breast-cancer-research.com/content/10.5/R90 2008, accessed Mar 2010.
15. Potten C, Owen G, Booth C: Intestinal stem cells protect their genome by segregation of their genome by selection of template DNA strands. J Cell Sci 115:2381-2388, 2002
16. Waghmare SK et al: Quantitative prolferation dynamics and random chromosome segregation of hair follicle stem cells. EMBO J 9:1309-1320, 2008
17. Sotiropoulou PA, Candi A, Blanpain C: The majority of multipotential epidermal stem cells do not protect their genome by asymmetrical chromosome segregation. Stem Cells 26:2964-2967, 2008
18. Watt FM, Jones PH: Expression and function of the keratinocyte integrins. Dev Suppl 185-192, 1993
19. Brash DE et al: Colonization of adjacent cell compartments by mutant keratinocytes. Semin Cancer Biol 3:97-102, 2005
20. Mackenzie IC, Zimmerman K, Peterson L: The pattern of cellular organization of human epidermis. J Invest Dermatol 76:459-461, 1981
21. Christophers E: Cellular architecture of the stratum corneum. J Invest Dermatol 56:165-169, 1971
22. Potten CS: The epidermal proliferative unit: The possible role of the central basal cell. Cell Tissue Kinet 7:77-88, 1974
23. Bickenbach JR, Mackenzie IC: Identification and behavior of label-retaining cells in hamster epithelia. J Invest Dermatol 82:618-622, 1984
24. Morris RJ, Fischer SM, Slaga TJ: Evidence that the centrally and peripherally located cells in the murine epidermal proliferative units are two distinct cell populations. J Invest Dermatol 84:277-281, 1985
25. Potten CS: Cell cycles in cell hierarchies. Int J Radiat Biol 49:257-258, 1986
26. Lavker RM, Sun TT: Heterogeneity in epidermal basal keratinocytes: Morphological and functional considerations. Science 215:1239-1241, 1982
27. Jones PH, Harper S, Watt FM: Stem cell patterning and fate in human epidermis. Cell 80:83-93, 1995
28. Gahzizadeh S, Taichman LB: Organization of stem cells and their progeny in human epidermis. J Invest Dermatol 124:367-372, 2005
29. Li A, Simmons PJ, Kaur P: Identification and isolation of candidate human keratinocyte stem cell based on cell surface phenotype. Proc Natl Acad Sci USA 95:3902-3907, 1998
30. Jensen KB, Watt FM: Single cell expression profiling of human epidermal stem and transit amplifying cells. Lrig1 is a regulator of stem cell quiescence. Proc Natl Acad Sci USA 103:11958-11963, 2006.
31. Jensen KB et al: Lrig1 expression defines a distinct multipotent stem ell population in mammalian epidermis. Cell Stem Cell 4:427-439, 2009
32. Clayton E et al: A single type of progenitor cell maintains normal epidermis. Nature 446:185-409, 2007
33. Ghazizadeh S, Taichman: LB: Multiple classes of stem cells in cutaneous epithelium: A lineage analysis of adult mouse skin. EMBO J 20:1215-1222, 2001
34. Fuchs E: Finding one's niche in the skin. Cell Stem Cell 4:499-502, 2009
35. Watt FM, Jensen KB: Epidermal stem cell diversity and quiescence. EMBO Mol Med 1:260-267, 2009
36. Koster MI, Kim S, Roop DR: p63 deficiency: A failure of lineage commitment of stem cell maintenance. J Invest Dermatol Symp Proc 10:118-123, 2005
37. Honeycutt KA, Koster MI, Roop DR: Genes involved in stem cell fate decisions and commitment to differentiation play a role in skin disease. J Invest Dermatol Symp Proc 9:261-268, 2004
38. Watt FM, Driskell RR: The therapeutic potential of stem cells. Philos Trans R Soc London B Biol Sci 365:155-163, 2010
39. Grabe N, Neuber K. Simulating psoriasis by altering transit amplifying cells. Bioinformatics 23:1309-1312, 2007
40. Green H: The birth of therapy with cultured cells. BioEssays 30:897-903, 2008
41. Limat A, Hunziker T: Use of epidermal equivalents generated from follicular outer root sheath cells in vitro for autologous grafting of chronic wounds. Cells Tissues Organs 172:79-85, 2002
42. Greenhalgh DA, Rothnagel JA, Roop DR: Epidermis: An attractive target tissue for gene therapy. J Invest Dermatol 103(S5):63S-69S, 1994
43. Ghazizadeh S, Taichman LB: Virus-mediated gene transfer for cutaneous gene therapy. Hum Gene Ther 11:2247-2251, 2000
44. Leachman SA et al: Therapeutic siRNA for dominant genetic skin disorders including pachyonychia congenital. J Dermatol Sci 3:151-157, 2008