Dosage and method of administration. Generally, the recommended initial dose of Micrurus antivenom is three to five vials. The drug is most effective if given before the onset of signs or symptoms of envenomation. An additional three to five vials may be given, depending on the severity of neurologic manifestations but not on body weight (children may require doses as large as or even larger than those for adults).
The recommended dose of exotic snake antivenom will vary. With other elapids, such as cobras, the antivenom is also more effective if given early in the course of the envenomation.
Treat all patients in an intensive care unit setting.
Before a skin test or antivenom administration, insert at least one and preferably two secure intravenous lines.
Perform a skin test for horse serum sensitivity, using a 1:10 dilution ...