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Antiviral drugs are used for a variety of infections, including herpes, hepatitis B and C, and influenza. Human immunodeficiency virus (HIV) infection was first reported in 1981. The search for effective anti-HIV treatment began in 1987 with zidovudine (AZT) as a single-agent regimen. In 1994, the first protease inhibitor, saquinavir, was introduced. More agents and different classes of antiretroviral agents were developed later (Table II–12).

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Table II-12 Antiviral and Antiretroviral Drugs

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