Poisoning & Drug Overdose provides practical advice for the
diagnosis and management of poisoning and drug overdose and concise
information about common industrial chemicals.
The manual is divided into four sections and an index. Section I
leads the reader through initial emergency management, including treatment
of coma, hypotension, and other common complications; physical and
laboratory diagnosis; and methods of decontamination and enhanced
elimination of poisons. Section II provides detailed information for
approximately 150 common drugs and poisons. Section III describes the
use and side effects of approximately 60 antidotes and therapeutic drugs. Section
IV describes the medical management of chemical spills and occupational
chemical exposures and includes a table of over 500 chemicals. The Index
is comprehensive and extensively cross-referenced.
The manual is designed to allow the reader to move quickly from section to
section, obtaining the needed information from each. For example, in
managing a patient with isoniazid intoxication, the reader will find
specific information about isoniazid toxicity in Section II,
practical advice for gut decontamination and management of complications
such as seizures in Section I, and detailed information about dosing
and side effects for the antidote pyridoxine in Section III.
Acknowledgments
The success of the first and second editions of this manual would not have
been possible without the combined efforts of the staff, faculty, and
fellows of the San Francisco Bay Area Regional Poison Control Center, to
whom I am deeply indebted. From its inception, this book has been a project
by and for our poison center; as a result, all royalties from its sale have
gone to our center's operating fund and not to any individual editor or
author.
In January 1997, four independent poison
control centers joined their talents to become the California Poison Control
System, administered by the University of California, San Francisco. With
the third, fourth, and fifth editions, the manual became a project of our
statewide system, bringing in new authors and editors.
On behalf of the authors and editors of the sixth edition,
my sincere thanks go to all those who contributed to one or more of the
first five editions:
Timothy E. Albertson, MD,
PhD
Judith A. Alsop, PharmD
Ilene Brewer Anderson, PharmD
Margaret Atterbury, MD
Georgeanne M. Backman
John Balmes, MD
Shireen Banerji, PharmD
James David Barry, MD
Charles E. Becker,
MD
Neal L. Benowitz, MD
Bruce Bernard, MD
David P. Betten, MD
Kathleen Birnbaum, PharmD
Paul D. Blanc, MD, MSPH
Stephen Born, MD
Christopher R. Brown, MD
Randall G. Browning, MD, MPH
James F.
Buchanan, PharmD
Alan Buchwald, MD
Cindy Burkhardt, PharmD
F.
Lee Cantrell, PharmD
Terry Carlson, PharmD
Gregory Cham, MD
Chulathida Chomchai, MD
Summon Chomchai, MD
Richard F. Clark, MD
Matthew D. Cook, MD
Delia Dempsey, MD
Chris Dutra, MD
Jo
Ellen Dyer, PharmD
Brent R. Ekins, PharmD
Andrew Erdman, MD
Gary Everson, PharmD
Thomas J. Ferguson, MD, PhD
Donna E. Foliart,
MD, MPH
Frederick Fung, MD
Mark J. Galbo, MS
Fabian Garza,
PharmD
Rick Geller, MD
Robert L. Goldberg, MD
Colin S. Goto,
MD
Gail M. Gullickson, MD
Christine A. Haller, MD
Jennifer
Hannum, MD
Patricia H. Hiatt, BS
B. Zane Horowitz, MD
Yao-min
Hung, MD
David L. Irons, PharmD
Leslie Isreal, DO, MPH
Gerald
Joe, PharmD
Jeffrey R. Jones, MPH, CIH
Thomas E. Kearney, PharmD
Kathryn H. Keller, PharmD
Michael T. Kelley, MD
Susan Y. Kim,
PharmD
Michael Kosnett, MD
Amy Kunihiro, MD
Grant D. Lackey,
PharmD
Chi-Leung Lai, PharmD
Rita Lam, PharmD
Shelly Lam,
PharmD
John P. Lamb, PharmD
Belle L. Lee, PharmD
Darrem Lew,
PharmD
Diane Liu, MD, MPH
Binh T. Ly, MD
Richard Lynton, MD
Beth Manning, PharmD
Anthony S. Manoguerra, PharmD
Kathy
Marquardt, PharmD
Timothy D. McCarthy, PharmD
Howard E. McKinney,
PharmD
Kathryn H. Meier, PharmD
Michael A. Miller, MD
Eileen
Morentz
Walter H. Mullen, PharmD
Stephen W. Munday, MD, MPH, MS
Nancy G. Murphy, MD
Frank J. Mycroft, PhD, MPH
Steve Offerman, MD
Kent R. Olson, MD
Michael O'Malley, MD, MPH
Gary Joseph Ordog, MD
John D. Osterloh, MD
Gary Pasternak, MD
Manish Patel, MD
Paul
D. Pearigen, MD
Cyrus Rangan, MD
Brett A. Roth, MD
Freda M.
Rowley, PharmD
Thomas R. Sands, PharmD
Aaron Schnier, MD
Jay
Schrader
Kerry Schwarz, PharmD
Dennis J. Shusterman, MD, MPH
Karl A. Sporer, MD
Jeffrey R. Suchard, MD
Winnie W. Tai, PharmD
David A. Tanen, MD
S. Alan Tani, PharmD
John H. Tegzes, VMD
R. Steven Tharratt, MD
Josef G. Thundiyil, MD, MPH
Ben Tsutaoka,
PharmD
Mary Tweig, MD
Peter H. Wald, MD, MPH
Michael J.
Walsh, PharmD
Jonathan Wasserberger, MD
Janet S. Weiss, MD
R.
David West, PharmD
Timothy J. Wiegand, MD
Saralyn R. Williams, MD
Olga F. Woo, PharmD
Evan T. Wythe, MD
Peter Yip, MD
Shoshana
Zevin, MD
We are also grateful for the numerous
comments and suggestions received from colleagues, students, and the
editorial staff at McGraw-Hill, which helped us to improve the manual with
each edition.
Kent R. Olson, MD, FACEP, FACMT,
FAACT
San Francisco, California
August 2011