Sections View Full Chapter Figures Tables Videos Annotate Full Chapter Figures Tables Videos Supplementary Content ++Table Graphic Jump Location|Download (.pdf)|PrintNormal Hormone Reference Rangesa,bTestSourceAges, Conditions, etcConventional UnitsConversion FactorSI UnitsCommentsAdrenocorticotropic hormone (ACTH) stimulation test (cosyntropin test): 0.25 mg of synthetic ACTH1-24 (cosyntropin) is administered IV or IM, and serum cortisol is measured at 0, 30, and 60 min. Normal response: peak cortisol >20 μg/dL (>540 nmol/L). A dose of 1 μg of ACTH will give a similar response in the normal individual (see Chapter 9).ACTHPlasmaMen7-50 pg/mL0.2221.55-11.1 pmol/LCollect in silicone-coated EDTA-containing tubes. Keep iced. Avoid contact with glass during collection and separation. Process immediately. Separate and freeze plasma in plastic tube at −20°C.Women5-27 pg/mL1.11-6 pmol/LChildrenPrepubertal 7-28 pg/mL1.55-6.2 pmol/LPostpubertal2-49 pg/mL0.44-10.78 pmol/LPost-dexamethasone suppression2-5 pg/mL0.4-1.1 pmol/LAldosteroneSerum (fasting)Sodium intake – 27.7300 mmol/d:Adult Levels in pregnant patients are three to four times higher.Upright am<28 ng/dL<776 pmol/L Upright pm<21 ng/dL<582 pmol/LSupine am3-16 ng/dL83.1-443 pmol/LAdrenal vein200-400 ng/dL5540-11,080 pmol/LUrineSodium diet––Collect 24-h specimen in 10 g boric acid to maintain pH <7.5. Refrigerate during collection.(100-300 mmol/d)Children:2-7 y≤5.7 μg/d 8-11 y≤10.2 μg/d 12-16 y≤15.6 μg/d Adult≤2.3-21 μg/d Post-fludrocortisone or intravenous saline infusion≤5.0 μg/dAlkaline phosphatase, bone specificSerum2-24 mo25.4-124.0 μg/L––IRMA; collect following an overnight fast; useful in Paget disease and osteoporosis; assay also known as Ostase; increased levels seen in states of high bone turnover (Paget disease, hyperthyroidism, osteoporosis).6-9 y 41-134.6 μg/L 10-13 yMales43.8-177.4 μg/LFemales 24.2-154.2 μg/L14-17 y Males 3.7-128 μg/L Females 110.5-75.2 μg/L Adult males 18-29 y 8.4-29.3 μg/L 30-39 y 7.7-21.3 μg/L 40-49 y 7.0-18.3 μg/L 60-68 y7.6-14.9 μg/L Adult females 18-29 y 4.7-17.8 μg/L 30-39 y 5.3-19.5 μg/L 40-49 y 5.0-18.8 μg/L 50-76 y5.6-29 μg/LAlpha subunitSerumMen<0.6 ng/mL ––RIA; used to assess gonadotropin hormone subunit secretion in pituitary adenomas.WomenPremenopausal <1.5 ng/mL Postmenopausal 0.9-3.3 ng/mL Hypothyroid<3.7 ng/mL Pregnant or hCG-producing tumor1.8-360 ng/mL3α-Androstenediol glucuronideSerumPrepubertal children 0.1-0.6 ng/mL 2.140.2-1.3 nmol/L Freeze serum and store at −20°C.Tanner II-III Male 0.19-1.64 ng/mL 0.41-3.51 nmol/L Female 0.33-2.44 ng/mL 0.71-5.22 nmol/L Adult Male 2.6-15 ng/mL 5.6-32.1 nmol/L Female0.6-3.0 ng/mL1.3-6.4 nmol/LAndrostenedioneSerumMen 3.4918-30 y 50-220 ng/dL 175-768 nmol/L 31-50 y 40-190 ng/dL 140-663 nmol/L 51-60 y50-220 ng/dL 175-768 nmol/L Women Follicular 35-250 ng/dL 122-873 nmol/L Midcycle 60-285 ng/dL 209-995 nmol/L Luteal 30-235 ng/dL 105-820 nmol/L Postmenopausal 20-75 ng/dL 70-262 nmol/LChildren 1-12 mo 6-78 ng/dL 21-272 nmol/L 1-4 y 5-51 ng/dL 17-178 nmol/L 5-9 y 6-115 ng/dL 21-401 nmol/L 10-13 y 12-221 ng/dL 42-771 nmol/L 14-17 y 22-225 ng/dL 77-785 nmol/L Tanner II-III Male 17-82 ng/dL 59-286 nmol/L Female 43-180 ng/dL 150-628 nmol/L Tanner IV-V Male 57-150 ng/dL 199-523 nmol/L Female... Your Access profile is currently affiliated with '[InstitutionA]' and is in the process of switching affiliations to '[InstitutionB]'. Please click ‘Continue’ to continue the affiliation switch, otherwise click ‘Cancel’ to cancel signing in. Get Free Access Through Your Institution Learn how to see if your library subscribes to McGraw Hill Medical products. Subscribe: Institutional or Individual Sign In Username Error: Please enter User Name Password Error: Please enter Password Forgot Password? Forgot Username? Sign in via OpenAthens Sign in via Shibboleth