Sections View Full Chapter Figures Tables Videos Full Chapter Figures Tables Videos Supplementary Content ++ ABCC8 ATP-binding cassette transporter sub-family C member 8ACE Angiotensin-converting enzymeADA American Diabetes AssociationADH Antidiuretic hormone (vasopressin)AGE Advanced glycation end productAGPAT 1-acylglycerol-3-phosphate-O-acyltransferase 2AKT/PKB AKR mouse tumor 8 kinase/protein kinase BAIRE Autoimmune regulatorALT Alanine aminotransferaseAMPK Adenosine monophosphate-activated protein kinaseAPS1 Autoimmune polyendocrinopathy syndrome type 1ATF6 Activating transcription factor 6BMIy Body mass indexcAMP Cyclic adenosine monophosphateCCK CholecystokininCEL Carboxyl-ester lipasecGMP Cyclic 3′,5′-guanosine monophosphateCIDEC Cell death-inducing DFFA-like effector CCSII Continuous subcutaneous insulin infusionCST Contraction stress testDCCT Diabetes Control and Complications TrialDIDMOAD Diabetes insipidus, diabetes mellitus, optic atrophy, deafness (Wolfram syndrome)DPP Diabetes Prevention ProgramDPP-4 Dipeptidyl peptidase 4DPT-1 Diabetes Prevention Trial-1EIF2AK3 Eukaryotic translation initiation factor 2-α kinase 3ER Endoplasmic reticulumFDA Food and Drug AdministrationFFA Free fatty acidFHR Fetal heart rateFoxo1 Forkhead box, subfamily O, member 1FOXP3 Forkhead box, subfamily P, member 3GABA Gamma-aminobutyric acidGAD Glutamic acid decarboxylaseGCK GlucokinaseGH Growth hormoneGHb GlycohemoglobinGHSR Growth hormone-secretagogue receptorGI Glycemic indexGIP Gastric inhibitory polypeptideGLIS3 Glioma-associated oncogene homolog—similar 3GLP-1 Glucagon-like peptide-1GLP-2 Glucagon-like peptide-2GLUT Glucose transporterGPCR G protein-coupled receptorGRPP Glicentin-related polypeptideGWAS Genome-wide association studyHDL High-density lipoproteinHLA Human leukocyte antigenHNF Hepatocyte nuclear factorhPL Human placental lactogenIA2 Insulinoma antigen 2IAA Insulin autoantibodyIAPP Islet amyloid polypeptideICA Islet cell antibodyIFG Impaired fasting glucoseIGF-1 Insulin-like growth factor 1IGT Impaired glucose toleranceIL-6 Interleukin-6INS InsulinIP3 Inositol 1,4,5-triphosphateIPEX Immunodysregulation polyendocrinopathy enteropathy, X-linkedIPF-1 Insulin promoter factor-1IRE1 Inositol-requiring enzyme 1IRS Insulin receptor substrateISL1 Islet transcription factor 1IUGR Intrauterine growth restrictionKPD Ketosis prone diabetesKCNJ11 Potassium inwardly-rectifying channel, subfamily J, member 11Kir6.2 Potassium channel, inwardly- rectifying 6.2LADA Latent autoimmune diabetes of adulthoodLBK1 Liver kinase B1LDL Low-density lipoproteinMAPK Mitogen-activated protein kinaseMODY Maturity-onset diabetes of the youngMHC Major histocompatibility complexmTOR Mammalian target of rapamycinNeuroD1 Neural differentiation factor 1Neurog3 Neural genesis factor 3NIH National Institutes of HealthNPH Neutral protamine hagedornNST Nonstress testPAI-1 Plasminogen activator inhibitor-1PAX4 Paired homeobox 4PCSK Proprotein convertase, subtilisin/kexinPDE5 Phosphodiesterase type 5PDX1 Pancreatic duodenal homeobox-1PERK Protein kinase R-like endoplasmic reticulum kinasePGC1α PPAR gamma coactivator-1αPNDM Permanent neonatal diabetes mellitusPOEMS Polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin changesPP Pancreatic polypeptidePPAR Peroxisome proliferator-activated receptorPTF1A Pancreatic transcription factor 1αPTP1b Protein tyrosine phosphatase 1bRFX6 Regulatory factor X-6RXR 9-cis-retinoic acid receptorSCL19A2 Solute carrier family 19 (thiamine transporter), member 2SOCS Suppressor of cytokine signalingSREBP1c Sterol regulatory element-binding protein 1cSSTR Somatostatin receptorSUR1 Sulfonylurea receptor 1TCF7L2 Transcription factor 7-like 2TGF-a Transforming growth factor-βTNDM Transient neonatal diabetes mellitusTNF-α Tumor necrosis factor-αUGDP University Group Diabetes ProgramUKPDS United Kingdom Prospective Diabetes StudyVEGF Vascular endothelial growth factorVLDL Very low ... Your MyAccess profile is currently affiliated with '[InstitutionA]' and is in the process of switching affiliations to '[InstitutionB]'. Please click ‘Continue’ to continue the affiliation switch, otherwise click ‘Cancel’ to cancel signing in. Get Free Access Through Your Institution Learn how to see if your library subscribes to McGraw Hill Medical products. Subscribe: Institutional or Individual Sign In Username Error: Please enter User Name Password Error: Please enter Password Forgot Username? Forgot Password? Sign in via OpenAthens Sign in via Shibboleth