Sections View Full Chapter Figures Tables Videos Annotate Full Chapter Figures Tables Videos Supplementary Content ++ ABCC8 ATP-binding cassette transporter sub-family C member 8ACE Angiotensin-converting enzymeADA American Diabetes AssociationADH Antidiuretic hormone (vasopressin)AGE Advanced glycation end productAGPAT 1-acylglycerol-3-phosphate-O-acyltransferase 2AKT/PKB AKR mouse tumor 8 kinase/protein kinase BAIRE Autoimmune regulatorALT Alanine aminotransferaseAMPK Adenosine monophosphate-activated protein kinaseAPS1 Autoimmune polyendocrinopathy syndrome type 1ATF6 Activating transcription factor 6BMIy Body mass indexcAMP Cyclic adenosine monophosphateCCK CholecystokininCEL Carboxyl-ester lipasecGMP Cyclic 3′,5′-guanosine monophosphateCIDEC Cell death-inducing DFFA-like effector CCSII Continuous subcutaneous insulin infusionCST Contraction stress testDCCT Diabetes Control and Complications TrialDIDMOAD Diabetes insipidus, diabetes mellitus, optic atrophy, deafness (Wolfram syndrome)DPP Diabetes Prevention ProgramDPP-4 Dipeptidyl peptidase 4DPT-1 Diabetes Prevention Trial-1EIF2AK3 Eukaryotic translation initiation factor 2-α kinase 3ER Endoplasmic reticulumFDA Food and Drug AdministrationFFA Free fatty acidFHR Fetal heart rateFoxo1 Forkhead box, subfamily O, member 1FOXP3 Forkhead box, subfamily P, member 3GABA Gamma-aminobutyric acidGAD Glutamic acid decarboxylaseGCK GlucokinaseGH Growth hormoneGHb GlycohemoglobinGHSR Growth hormone-secretagogue receptorGI Glycemic indexGIP Gastric inhibitory polypeptideGLIS3 Glioma-associated oncogene homolog—similar 3GLP-1 Glucagon-like peptide-1GLP-2 Glucagon-like peptide-2GLUT Glucose transporterGPCR G protein-coupled receptorGRPP Glicentin-related polypeptideGWAS Genome-wide association studyHDL High-density lipoproteinHLA Human leukocyte antigenHNF Hepatocyte nuclear factorhPL Human placental lactogenIA2 Insulinoma antigen 2IAA Insulin autoantibodyIAPP Islet amyloid polypeptideICA Islet cell antibodyIFG Impaired fasting glucoseIGF-1 Insulin-like growth factor 1IGT Impaired glucose toleranceIL-6 Interleukin-6INS InsulinIP3 Inositol 1,4,5-triphosphateIPEX Immunodysregulation polyendocrinopathy enteropathy, X-linkedIPF-1 Insulin promoter factor-1IRE1 Inositol-requiring enzyme 1IRS Insulin receptor substrateISL1 Islet transcription factor 1IUGR Intrauterine growth restrictionKPD Ketosis prone diabetesKCNJ11 Potassium inwardly-rectifying channel, subfamily J, member 11Kir6.2 Potassium channel, inwardly- rectifying 6.2LADA Latent autoimmune diabetes of adulthoodLBK1 Liver kinase B1LDL Low-density lipoproteinMAPK Mitogen-activated protein kinaseMODY Maturity-onset diabetes of the youngMHC Major histocompatibility complexmTOR Mammalian target of rapamycinNeuroD1 Neural differentiation factor 1Neurog3 Neural genesis factor 3NIH National Institutes of HealthNPH Neutral protamine hagedornNST Nonstress testPAI-1 Plasminogen activator inhibitor-1PAX4 Paired homeobox 4PCSK Proprotein convertase, subtilisin/kexinPDE5 Phosphodiesterase type 5PDX1 Pancreatic duodenal homeobox-1PERK Protein kinase R-like endoplasmic reticulum kinasePGC1α PPAR gamma coactivator-1αPNDM Permanent neonatal diabetes mellitusPOEMS Polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin changesPP Pancreatic polypeptidePPAR Peroxisome proliferator-activated receptorPTF1A Pancreatic transcription factor 1αPTP1b Protein tyrosine phosphatase 1bRFX6 Regulatory factor X-6RXR 9-cis-retinoic acid receptorSCL19A2 Solute carrier family 19 (thiamine transporter), member 2SOCS Suppressor of cytokine signalingSREBP1c Sterol regulatory element-binding protein 1cSSTR Somatostatin receptorSUR1 Sulfonylurea receptor 1TCF7L2 Transcription factor 7-like 2TGF-a Transforming growth factor-βTNDM Transient neonatal diabetes mellitusTNF-α Tumor necrosis factor-αUGDP University Group Diabetes ProgramUKPDS United Kingdom Prospective Diabetes StudyVEGF Vascular endothelial growth factorVLDL Very low ... Your Access profile is currently affiliated with [InstitutionA] and is in the process of switching affiliations to [InstitutionB]. Please select how you would like to proceed. Keep the current affiliation with [InstitutionA] and continue with the Access profile sign in process Switch affiliation to [InstitutionB] and continue with the Access profile sign in process Get Free Access Through Your Institution Learn how to see if your library subscribes to McGraw Hill Medical products. Subscribe: Institutional or Individual Sign In Error: Incorrect UserName or Password Username Error: Please enter User Name Password Error: Please enter Password Sign in Forgot Password? Forgot Username? Download the Access App: iOS | Android Sign in via OpenAthens Sign in via Shibboleth You already have access! Please proceed to your institution's subscription. Create a free profile for additional features.