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ADAAdenosine deaminase

ADCC Antibody-dependent cell-mediated cytotoxicity

AIDSAcquired immunodeficiency syndrome

APC Antigen-presenting cell

BCR B-cell receptor

BTK Bruton’s tyrosine kinase

C1, C2, etc Complement factor 1, complement factor 2, etc

cAMP Cyclic adenosine monophosphate

CCR5 CC-subfamily chemokine receptor 5

CD Clusters of differentiation

CD4 Helper T-cell subset

CD8 Cytotoxic T-cell subset

CTL Cytotoxic lymphocyte

CXCR5 CXC-subfamily chemoreceptor 5

F(ab) Antigen-binding fragment

Fc Crystallizable fragment

FcεRI High-affinity IgE receptor

FcγR Fc gamma receptor

GM-CSFGranulocyte-macrophage colony-stimulating factor

HBV Hepatitis B virus

HCV Hepatitis C virus

HIVHuman immunodeficiency virus

HPV Human papillomavirus

HSV Herpes simplex virus

HZV Herpes zoster virus

ICAM-1 Intercellular adhesion molecule-1

IFN-γ Interferon-γ

Ig Immunoglobulin

IVIG Intravenous immunoglobulin

IL-1, IL-2, etc Interleukin-1, interleukin-2, etc.

JAK Janus kinase

JC Jakob–Creutzfeldt

LAK cell Lymphokine-activated killer cell

LPS Lipopolysaccharide

MAC Mycobacterium avium complex

MHCMajor histocompatibility complex

NADPHNicotinamide adenine dinucleotide phosphate

NK Natural killer cells

PAF Platelet-activating factor

PGDProstaglandin D

PNP Purine nucleoside phosphorylase

PTK Protein tyrosine kinase

RAG Recombination-activating gene

RANTES Chemokine regulated on activation normal T expressed and secreted

RAST Radioallergosorbent test

SCID Severe combined immunodeficiency disease

TAME  N-α-p-tosyl-l-arginine methylester-esterase

TCR T-cell receptor

TH1 Helper T 1 subset

TH2 Helper T 2 subset

TH17 Helper T subset secreting IL-17

TREG Helper T subset with regulatory function

Tr1 Regulatory T-cell subset

TLR Toll-like receptor

TNF Tumor necrosis factor

TSH Thyroid-stimulating hormone

V-CAM-1 Vascular cell adhesion molecule-1

VIP Vasoactive intestinal peptide

XLA X-linked agammaglobulinemia

XSCID X-linked severe combined immunodeficiency disease

ZAP-70 Protein tyrosine kinase ZAP-70

The function of the immune system is to protect the host from invasion of foreign organisms by distinguishing “self” from “nonself.” Such a system is necessary for survival. A well-functioning immune system not only protects the host from ...

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