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Normal moles should be well-demarcated, symmetric, and uniform in contour and color
May darken and grow during pregnancy
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Physical examination must take precedence over the history
Benign nevi must be differentiated from malignant melanomas
Signs of melanoma can be remembered by the mnemonic: ABCDE with A = Asymmetry; B = Border irregularity; C = Color variegation; D = Diameter greater than 6 mm; E = Evolution
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None required; benign moles have a normal natural history
Regular mole screening is not an evidence-based recommendation for all adults although rates of such screening continue to rise
Moles that are atypical in any fashion that suggests melanoma should be excised and submitted for pathologic examination