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Extensive or prolonged inhalation of free silica (silicon dioxide) particles (sandblasters, foundry, granite and stone cutting, molding, ceramics) in the respirable range (0.3–5 mcm)
Small, rounded opacities (silicotic nodules) throughout the lung
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Simple silicosis is usually asymptomatic without effect on routine pulmonary function tests
Complicated silicosis presents with large conglomerate densities in the upper lung; dyspnea with obstructive and restrictive pulmonary dysfunction is common
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