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For further information, see CMDT Part 25-15: Sleep-Wake Disorders

Key Features

  • Sleep terror, nightmares, sleepwalking, and enuresis are more common in children than in adults

  • Sleep terror

    • Abrupt, terrifying arousal from sleep

    • Usually seen in preadolescent boys, although it may occur in adults

    • Distinct from sleep panic attacks

  • Nightmares occur during REM sleep, unlike sleep terror, which occurs in stage 3 or 4

  • Sleepwalking

    • Includes ambulation or other intricate behaviors while asleep, with amnesia for the event

    • Mostly affects children ages 6–12 years

    • Episodes occur during stage 3 or 4 sleep in the first third of the night and in REM sleep in the later sleep hours

    • In the elderly, may be a sign of dementia

    • May be an idiosyncratic reactions to drugs (eg, marijuana, alcohol) and medical conditions (eg, partial complex seizures) in adults

  • Enuresis

    • Involuntary micturition during sleep occurring in a patient who usually has control

    • More common in children, usually in the 3–4 hours after bedtime, but not limited to a specific stage of sleep

Clinical Findings

  • Sleep terror

    • Abrupt, terrifying arousal from sleep

    • Fear, sweating, tachycardia, and confusion for several minutes

    • Confusion during the event and amnesia after it

Diagnosis

  • Sleepwalking is confirmed by a sleep study

Treatment

  • For sleep terrors and sleepwalking: benzodiazepines (diazepam, 5–20 mg orally at bedtime, suppresses stage 3 and 4 sleep)

  • For enuresis

    • Desmopressin nasal spray is likely the treatment of choice for nocturnal enuresis

    • Imipramine, 50–100 mg orally at bedtime

    • Behavioral approaches (eg, bells that ring when the pad gets wet) have also been successful

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