SGLT2-inhibitors may be added to standard care in the well-selected patient. Corticosteroids for reducing proteinuria and slowing progression; however, may be considered for patients with GFR greater than 30 mL/min/1.73 m2 and persistent proteinuria greater than 1 g/day despite maximal ACE inhibitor or ARB.
Cheung CK et al. J Clin Med. [PMID: 34200024]
Mineralocorticoid receptor antagonism can be considered for blood pressure and proteinuria management in type 2 diabetes mellitus with careful monitoring for hyperkalemia.
Hahr AJ et al. Am J Kidney Dis. [PMID: 34600745]