OCCLUSIVE DISEASE: FEMORAL & POPLITEAL ARTERIES
Dual treatment with rivaroxaban 2.5 mg orally twice daily and aspirin 81 mg orally daily has been shown to reduce limb-related events, major amputation, and cardiovascular events.
Bauersachs RM et al. J Am Coll Cardiol. [PMID: 34010631]
For patients who cannot tolerate a beta-blocker or who need a second agent to control the hypertension, intravenous calcium channel blocker infusions such as nicardipine are an alternative. Start nicardipine 5 mg/hour intravenously and titrate the infusion to the desired effect.
Bossone E et al. Nat Rev Cardiol. [PMID: 33353985]