Skip to Main Content

For further information, see CMDT Part 29-10: Riboflavin (B2) Deficiency

Key Features

  • Usually occurs in combination with other vitamin deficiencies

  • Caused by dietary inadequacy, interactions with medications, alcoholism, and other causes of protein-calorie undernutrition

Clinical Findings

  • Cheilosis, angular stomatitis, glossitis

  • Seborrheic dermatitis

  • Weakness

  • Corneal vascularization

  • Anemia


  • Measure serum levels of the riboflavin-dependent enzyme erythrocyte glutathione reductase. Activity coefficients > 1.2–1.4 suggest riboflavin deficiency

  • Urinary riboflavin excretion and serum levels of plasma and red blood cell flavins can also be measured


  • Riboflavin, 5–15 mg orally once daily, until clinical findings resolve

Pop-up div Successfully Displayed

This div only appears when the trigger link is hovered over. Otherwise it is hidden from view.