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For further information, see CMDT Part 24-10: Intracranial & Spinal Mass Lesions

Key Features

Essentials of Diagnosis

  • Personality changes, intellectual decline, emotional lability

  • Seizures, headaches, nausea

  • Increased intracranial pressure in some patients

  • Neuroradiologic evidence of space-occupying lesion

General Considerations

  • About one-third of all primary intracranial neoplasms (Table 24–4) are meningiomas; a quarter are gliomas

  • The remainder are

    • Pituitary adenomas

    • Neurofibromas

    • Other tumors

  • Certain tumors (eg, neurofibromas, hemangioblastomas, and retinoblastomas) have a familial basis

  • May lead to a generalized disturbance of cerebral function and symptoms of increased intracranial pressure

Table 24–4.Primary intracranial tumors (listed by major histology grouping and by incidence within each group).

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