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For further information, see CMDT Part 24-31: Mononeuropathies

Key Features

  • May occur in persons with diabetes mellitus or from compression by retroperitoneal neoplasms or hematomas

  • May also result from pressure from the inguinal ligament when the thighs are markedly flexed and abducted, as in the lithotomy position

  • The neuropathy may be asymptomatic, resolve rapidly and spontaneously, or become progressively more disabling

Clinical Findings

  • Weakness and wasting of the quadriceps muscle

  • Sensory impairment over the anteromedian aspect of the thigh and sometimes also of the leg to the medial malleolus

  • Depressed or absent knee jerk


  • Electromyography and nerve conduction velocities are often indispensable for accurate localization of the focal lesion


  • Improvement may occur if any compression is relieved

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