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Symptoms of excess vitamin B6 supplementation can be similar to those of vitamin B6 deficiency. A sensory neuropathy, at times irreversible, occurs in patients receiving large doses of vitamin B6 (200–2000 mg/day).

Merigliano  C  et al. The relationship between vitamin B6, diabetes and cancer. Front Genet. 2018;9:388.
[PubMed: 30271425]  

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