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Which of the following is a live attenuated virus?

A. Human papillomavirus (HPV)

B. Hepatitis B

C. Varicella

D. Haemophilus influenzae type B (Hib)

Answer: C

Human papillomavirus (HPV) is a recombinant vaccine containing virus-like particles (VLPs) but is an inactivated viral vaccine. Hepatitis B is an inactivated viral vaccine. Varicella is a live attenuated virus. Haemophilus influenzae type B (Hib) is an inactivated conjugated polysaccharide vaccine.

Reference: Centers for Disease Control and Prevention (CDC). Recommended Immunization Schedule for Children and Adolescents Aged 18 Years or Younger, United States, 2020. CDC website. https://www.cdc.gov/vaccines/schedules/hcp/imz/child-adolescent.html Accessed March 26, 2020.

What is the current recommendation for a baby born to a mother with hepatitis B (Hep B)?

A. Give Hep B vaccine within 12 hours of birth and monitor liver function tests for signs of infection.

B. Give Hep B vaccine and hepatitis B immune globulin (HBIG) within 12 hours of birth.

C. Do not give Hep B vaccine as baby is already probably infected.

D. Give Hep B vaccine within 12 hours of birth and hepatitis B immune globulin (HBIG) after 7 days.

Answer: B

The current recommendations for a baby born to a mother with hepatitis B is to give the Hep B vaccine after birth and give HBIG within 12 hours of birth. These infants should be tested for hepatitis B surface antigen (HBsAg) and antibody to HBsAg at age 9 months (or 1-2 months after completion of the 3-dose hepatitis B series which is usually completed at 6 months). If the mother's Hep B status is unknown, the baby should get Hep B vaccine within 12 hours of birth, and the mother's hepatitis B status should be assessed as soon as possible. If the mother's status is positive or still unknown, give HBIG as soon as possible but no later than 7 days. It would be incorrect to either not give the Hep B vaccine or to monitor for signs of liver dysfunction without giving HBIG.

Reference: Centers for Disease Control and Prevention (CDC). Recommended Immunization Schedule for Children and Adolescents Aged 18 Years or Younger, United States, 2020. CDC website. https://www.cdc.gov/vaccines/schedules/hcp/imz/child-adolescent.html Accessed March 26, 2020

Which of the following unvaccinated adolescents should receive the HPV vaccine series?

A. A healthy 12-year-old female

B. A ...

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