Sections View Full Chapter Figures Tables Videos Annotate Full Chapter Figures Tables Videos Supplementary Content + Download Section PDF Listen ++ For further information, see CMDT Part 33-05: Clostridial Diseases + Key Features Download Section PDF Listen +++ ++ C sordellii is a rare cause of endometritis and toxic shock syndrome following childbirth Fatal cases of uterine infection following medically induced abortion with mifepristone have been reported + Clinical Findings Download Section PDF Listen +++ ++ Abdominal pain Absence of fever Onset of illness was within 4–5 days of ingestion of mifepristone Clinical course is fulminant Infection appeared to be limited to the uterus, which shows Necrosis Edema Hemorrhage Acute inflammatory changes + Diagnosis Download Section PDF Listen +++ ++ Tachycardia, severe hypotension, capillary leak syndrome with edema Profound leukocytosis, hemoconcentration + Treatment Download Section PDF Listen +++ ++ Early recognition Aggressive resuscitation from shock Immediate surgical debridement with hysterectomy Administration of an antimicrobial active against C sordellii, including Penicillin Ampicillin Macrolide Clindamycin Tetracycline Metronidazole