Sections View Full Chapter Figures Tables Videos Annotate Full Chapter Figures Tables Videos Supplementary Content + Download Section PDF Listen ++ For further information, see CMDT Part 29-10: Riboflavin (B2) Deficiency + Key Features Download Section PDF Listen +++ ++ Almost always occurs in combination with deficiencies of other vitamins Caused by dietary inadequacy, interactions with a variety of medications, alcoholism, and other causes of protein-calorie undernutrition + Clinical Findings Download Section PDF Listen +++ ++ Cheilosis, angular stomatitis, glossitis Seborrheic dermatitis Weakness Corneal vascularization Anemia + Diagnosis Download Section PDF Listen +++ ++ Measure serum levels of the riboflavin-dependent enzyme erythrocyte glutathione reductase. Activity coefficients > 1.2–1.4 suggest riboflavin deficiency Urinary riboflavin excretion and serum levels of plasma and red blood cell flavins can also be measured + Treatment Download Section PDF Listen +++ ++ Riboflavin, 5–15 mg orally once daily, until clinical findings are resolved