Sections View Full Chapter Figures Tables Videos Annotate Full Chapter Figures Tables Videos Supplementary Content + Download Section PDF Listen ++ For further information, see CMDT Part 20-50: Palindromic Rheumatism + Key Features Download Section PDF Listen +++ ++ Frequent recurring attacks at irregular intervals of acutely inflamed joints In some patients, palindromic rheumatism is a prodrome of rheumatoid arthritis + Clinical Findings Download Section PDF Listen +++ ++ Periarticular pain with swelling Attacks cease within several hours to several days Knee and fingers are most commonly affected, but any peripheral joint may be involved Although hundreds of attacks may take place over a period of years, there is no permanent articular damage + Diagnosis Download Section PDF Listen +++ ++ Clinical Laboratory findings are usually normal + Treatment Download Section PDF Listen +++ ++ Nonsteroidal anti-inflammatory drugs are usually all that is required during the attacks Hydroxychloroquine may be of value in preventing recurrences