Sections View Full Chapter Figures Tables Videos Annotate Full Chapter Figures Tables Videos Supplementary Content + Download Section PDF Listen ++ For further information, see CMDT Part 9-21: Diffuse Interstitial Pneumonias + Key Features Download Section PDF Listen +++ ++ Clinical presentation and features are similar to usual interstitial pneumonia (UIP) but with distinct pathologic findings and better prognosis The median survival is > 10 years + Clinical Findings Download Section PDF Listen +++ ++ Onset at age 45–55 with slight female predominance Presents as dyspnea and cough over months; otherwise, presentation is similar to that of UIP + Diagnosis Download Section PDF Listen +++ ++ Radiographically, may be indistinguishable from UIP High-resolution CT finding typically shows bilateral areas of ground-glass attenuation and fibrosis with rare honeycombing Biopsy shows varying degrees of patchy inflammation and fibrosis, which are uniform in time. Honeycombing is scant See Table 9–17 + Treatment Download Section PDF Listen +++ ++ Corticosteroids are thought to be effective, but no prospective clinical studies have been published Prognosis is good overall, but it depends on the degree of fibrosis at diagnosis