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Sinusitis, bronchitis, otitis and, rarely, pneumonia
Bacteremia and meningitis have also been reported in immunocompromised patients
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Culture
The organism frequently colonizes the respiratory tract, and differentiation of colonization from infection can be difficult
If M catarrhalis is the predominant isolate, therapy should be directed against it
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Amoxicillin-clavulanate, ampicillin-sulbactam, trimethoprim-sulfamethoxazole, ciprofloxacin, and second- and third-generation cephalosporins
Treatment is similar to that for Haemophilus infections (see Haemophilus Infections)
Typically produces beta-lactamase and, therefore, is usually resistant to ampicillin and amoxicillin