Sections View Full Chapter Figures Tables Videos Annotate Full Chapter Figures Tables Videos Supplementary Content + Download Section PDF Listen ++ For further information, see CMDT Part 24-01: Headache + Key Features Download Section PDF Listen +++ ++ Constant daily headaches that are often vise-like or tight in quality but not pulsatile May be exacerbated by emotional stress, fatigue, noise, or glare Patients also frequently complain of pericranial tenderness, poor concentration and other nonspecific symptoms + Clinical Findings Download Section PDF Listen +++ ++ Usually generalized May be most intense about the neck or back of the head Not associated with focal neurologic symptoms + Diagnosis Download Section PDF Listen +++ ++ Diagnosis is made after exclusion of other causes of headache (see individual diagnoses, eg, Sinusitis, Acute) + Treatment Download Section PDF Listen +++ ++ Therapeutic approach similar to that of migraine, except triptans and ergotamines are not indicated (see Headache, Migraine) Tricylcic antidepressants such as amitriptyline are supported for headache prophylaxis by randomized trial evidence and often are tried first Behavioral therapies that may be effective include biofeedback and relaxation training Treatment of comorbid anxiety or depression