Skip to Main Content

For further information, see CMDT Part 22-14: Nephritic Spectrum Glomerular Diseases

Key Features

Essentials of Diagnosis

  • Hematuria, subnephrotic proteinuria

  • Red cell casts pathognomonic but not required for diagnosis

  • Dependent edema and hypertension

  • Acute kidney injury

General Considerations

  • A relatively uncommon cause of acute kidney injury (AKI), ~5% of cases of hospitalized patients with AKI

  • Acute glomerulonephritis usually signifies an inflammatory process causing kidney dysfunction over days to weeks that may or may not resolve (Table 22–7)

  • Inflammatory glomerular lesions include mesangioproliferative, focal and diffuse proliferative, and crescentic lesions

  • Rapidly progressive acute glomerulonephritis can cause permanent damage to glomeruli if not identified and treated rapidly

Table 22–7.Classification and findings in glomerulonephritis: nephritic spectrum presentations.

Pop-up div Successfully Displayed

This div only appears when the trigger link is hovered over. Otherwise it is hidden from view.