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For further information, see CMDT Part 9-27: Pulmonary Vasculitis
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Idiopathic vasculitis of small- and medium-sized arteries seen in patients with symptoms of asthma
Affects multiple organ systems, most commonly skin and lung, but heart, gastrointestinal tract, and peripheral nerves may also be affected
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Usually requires corticosteroids (prednisone, 1 mg/kg/day, tapering over 3–6 months) and cyclophosphamide (1–2 mg/kg/day, until complete remission is obtained and then tapered slowly)
Replace cyclophosphamide with methotrexate or azathioprine for maintenance therapy