++
For further information, see CMDT Part 33-27: Chancroid
++
++
Initial lesion at the site of inoculation is a vesicopustule that breaks down to form a painful, soft ulcer with a necrotic base, surrounding erythema, and undermined edges
Multiple lesions, started by autoinoculation, and inguinal lymphadenitis often develop
Lymphadenitis
Usually unilateral
Consists of tender, matted nodes of moderate size with overlying erythema
Nodes may become fluctuant and rupture spontaneously
With lymph node involvement, fever, chills, and malaise may develop
Balanitis and phimosis are frequent complications in men
Women may have no external signs of infection
++
++
A single dose of either azithromycin, 1 g orally, or ceftriaxone, 250 mg intramuscularly, is effective
Effective multiple-dose regimens
Erythromycin, 500 mg four times daily orally for 7 days
Ciprofloxacin, 500 mg twice daily orally for 3 days