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For further information, see CMDT Part 33-31: Anaerobic Infections
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Most cases of anaerobic or microaerophilic streptococcal endocarditis can be effectively treated with 12–20 million units of penicillin G intravenously daily for 4–6 weeks
However, optimal therapy for other types of anaerobic bacterial endocarditis must rely on laboratory guidance
Metronidazole, 500 mg every 8 hours intravenously, should be used if Bacteroides species is identified