Older persons live longer and healthier lives than ever before. Persons over the age of 85 are the most rapidly growing segment of the population, increasing from 6.7 million in 2020, to 8.9 million in 2030, and to 18 million in 2050. Americans over age 65 will account for 20% of the population by 2030. Most clinicians will spend half or more of their time caring for older adults. Older persons vary widely in health status, prognosis, and preferences for care. Many persons in their 60s are healthy and can expect to live another 30 years or longer. Yet, chronic diseases that will cause disability and death will develop in nearly all older persons. Therefore, clinicians caring for older adults must have skills in managing multiple comorbidities and wisely guiding the patient in both “curative” and “supportive” care.