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NON-BOTANICAL DIETARY SUPPLEMENTS
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In the 7-year follow-up to the KUDOS study, in which mothers received either 600 mg/day of DHA or a placebo beginning at 14.5 weeks of gestation until delivery, no consistent long-term benefits were sustained into childhood. In a 2019 study, supplementation with 900 mg omega-3 fatty acids during early pregnancy did not result in a lower incidence of early preterm delivery or a higher incidence of interventions in postterm deliveries.
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A clinical trial of CoQ10 (200 mg) and vitamin E (400 international units) in 89 patients with polycystic ovarian syndrome found benefit on serum fasting blood sugar and insulin levels, as well as insulin resistance and total testosterone levels.
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Melatonin given as a nightly dose of 3 mg did not prevent delirium in non-intensive care unit hospitalized patients or improve subjective or objective sleep.
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The benefits of acupuncture in managing postoperative pain were shown in a 2019 study of abdominal surgery.
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A pilot study found that intraoperative laser acupuncture stimulation of P6 acupoints combined with antiemetic medication prophylaxis decreased postoperative nausea and rescue antiemetic medication need in patients who underwent a laparoscopic cholecystectomy.
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In 2020, Centers for Medicare & Medicaid Services approved coverage of acupuncture for Medicare patients with chronic low back pain. Many other insurance providers cover acupuncture.