I want to thank Morton Swartz, the former Chief of Infectious Diseases at the Massachusetts General Hospital, for inspiring my love of infectious diseases, and Drs. James McGuigan, the former Chairman of the Department of Medicine at the University of Florida, and Tom Stossel, Professor of Medicine at the Harvard Medical School, who have patiently mentored me throughout my career. I also thank Dr. Hernan Prieto, Assistant Professor of Orthopedics at the University of Florida for his up-to-date information on prosthetic joint infections. I appreciate the excellent and timely contributions by my colleagues and friends, Drs. Daniel Lew, Sankar Swaminathan, and Bernard Hirschel. Finally, I want to thank James Shanahan of McGraw-Hill for his continued support and guidance.