Sections View Full Chapter Figures Tables Videos Annotate Full Chapter Figures Tables Videos Supplementary Content + Download Section PDF Listen ++ For further information, see CMDT Part 33-17: Salmonellosis + Key Features Download Section PDF Listen +++ ++ This complication tends to occur in immunocompromised persons, eg, HIV-infected individuals, who typically have bacteremia without an obvious source + Clinical Findings Download Section PDF Listen +++ ++ May be manifested by prolonged or recurrent fevers or by local infection in bone, joints, pleura, pericardium, lungs, or other sites Gastrointestinal symptoms not a prominent feature Mycotic abdominal aortic aneurysms may be a complication + Diagnosis Download Section PDF Listen +++ ++ Serotypes other than Salmonella typhi usually are isolated in culture of blood, bone marrow, or site of infection + Treatment Download Section PDF Listen +++ ++ Treatment is the same as for typhoid fever (see Enteric Fever [Typhoid fever]) plus drainage of any abscesses In HIV-infected patients, relapse is common, and lifelong suppressive therapy may be needed Ciprofloxacin, 500 mg twice daily orally, is effective both for treatment of acute infection and for suppression of recurrence Drug-resistant (fluoroquinolones and ceftriaxone) strains are increasing in prevalence