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About 10% of lymphomas present in the head and neck. Multiple rubbery nodes, especially in young adults or in patients who have AIDS, are suggestive of this disease. A thorough physical examination may demonstrate other sites of nodal or organ involvement. FNA biopsy may be diagnostic, but open biopsy is often required to determine architecture and an appropriate treatment course.

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Oishi  N  et al. Head and neck lymphomas in HIV patients: a clinical perspective. Int Arch Otorhinolaryngol. 2017 Oct;21(4):399–407.
[PubMed: 29018505]
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Overgaard  J  et al. The Danish Head and Neck Cancer database. Clin Epidemiol. 2016 Oct 25;8:491–6.
[PubMed: 27843342]

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