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Chapter 35. Hepatitis Viruses

A 24-year-old woman in New York City is admitted to the hospital because of jaundice. On workup, she is found to have HCV infection. The major risk factor for HCV infection in the United States is

(A) Tattoos

(B) Injecting drug use

(C) Blood transfusion

(D) Sexual activity

(E) Working in health care occupations

Which of the following exposures poses a risk for hepatitis infection?

(A) A nurse sustains a needlestick while drawing up insulin to administer to an HBV-infected patient with diabetes.

(B) While cleaning the bathroom, a housekeeper’s intact skin has contact with feces.

(C) An operating room technician with chapped and abraded hands notices blood under his gloves after assisting in an operation on a patient with HCV infection.

(D) A child drinks out of the same cup as her mother, who has an HAV infection.

(E) A shopper eats a sandwich prepared by a worker with an asymptomatic HBV infection.

An epidemic of jaundice caused by HEV occurred in New Delhi. HEV is

(A) Found in rodents and pigs

(B) A major cause of bloodborne hepatitis

(C) The cause of a disease that resembles hepatitis C

(D) Capable of establishing chronic infections

(E) Associated with an increased risk of liver cancer

HDV (delta agent) is found only in patients who have either acute or chronic infection with HBV. Which of the following is most correct?

(A) HDV is a defective mutant of HBV.

(B) HDV depends on HBV surface antigen for virion formation.

(C) HDV induces an immune response indistinguishable from that induced by HBV.

(D) HDV is related to HCV.

(E) HDV contains a circular DNA genome.

A 23-year-old woman is planning a 1-year trip through Europe, Egypt, and the Indian subcontinent and receives a vaccine for hepatitis A. The current hepatitis A vaccine is

(A) A live attenuated virus vaccine


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