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Key Features

  • Anaerobic bacteremia usually originates from the

    • Gastrointestinal tract

    • Oropharynx

    • Pressure injuries

    • Female genital tract

  • Endocarditis resulting from anaerobic and microaerophilic streptococci and bacteroides (rare) originates from the same sites

Clinical Findings

  • Related to site of original and metastatic infection

Diagnosis

  • Culture of blood and affected tissues

Treatment

  • Most cases of anaerobic or microaerophilic streptococcal endocarditis can be effectively treated with 12–20 million units of penicillin G intravenously daily for 4–6 weeks

  • However, optimal therapy for other types of anaerobic bacterial endocarditis must rely on laboratory guidance

  • Metronidazole, 500 mg every 8 hours intravenously, should be used if Bacteroides species is identified

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